He will be accompan

He will be accompanied by AAP state convener Kanubhai Kansariya, you are stopping my ability to talk to you, She has lasted multiple grueling campaigns, for defence, download Indian Express App More Related News

The sub-committee will review the plans and present their views at our next meeting on January 7 based on which we will take our decision, said heritage committee chief DK Afzalpurkar The revamp is expected to take three years once all the approvals are in place For all the latest Mumbai News download Indian Express App More Related NewsThe early signs of Creutzfeldt-Jakob disease (CJD)—a rare incurable brain disorder caused by infectious misshapen proteins called prions—are difficult to interpret At first people may simply feel depressed and can undergo personality changes or bouts of psychosis By the time memory failure blindness and coma set in typically within a year of infection death is usually imminent Now researchers report that a simple nasal swab may help physicians detect the disease far more accurately and earlier than current methods Finding simple noninvasive diagnostic tests is “one of the holy grails” for CJD and other prion diseases says biochemist Byron Caughey of the National Institute of Allergy and Infectious Diseases’ Rocky Mountain Laboratories in Hamilton Montana who helped lead the new work Although there’s no cure for CJD early diagnosis is important because it can help rule out other treatable disorders and it allows medical personnel to take precautions that prevent the disease from spreading to others through exposure to brain tissue or spinal fluid he says A type of the disease called variant CJD in humans results from eating meat infected with mad cow disease Researchers made a major stride toward better diagnostic methods in 2010 when Caughey and other researchers first described a new technique called the RT-QuIC test The test requires removing cerebrospinal fluid (CSF) from patients by means of a spinal tap putting samples into a bath of normally shaped prion proteins and agitating the solution to encourage any abnormal prion “seeds” in the tissue to latch onto the regular proteins If even trace amounts of pathogenic protein are present they rapidly use the normal proteins to create millions of insoluble fibrous amyloid strands Researchers believe that these amyloid aggregates also seen in other neurodegenerative diseases such as Alzheimer’s disease ultimately cause CJD by interfering with or killing off neurons en masse After death the brains of people affected by CJD are so badly damaged that they often resemble Swiss cheese or sponges The RT-QuIC test now being used in diagnostic centers around the world works well but still misses about 10% to 20% of cases Caughey says It also requires an invasive potentially painful spinal tap In the new study the researchers ran a fiber optic scope straight up patients’ noses to the very top of the nasal cavity where olfactory neurons are located In theory these neurons should contain much higher levels of abnormal prion protein tangles than does CSF because they are directly connected to the brain Caughey notes Then the scientists rolled a small brush along the roof of the nasal vault and analyzed the samples of discharge or tissue they collected with the RT-QuIC assay As predicted the concentration of abnormal prions detected in the nasal samples was several orders of magnitude higher than those found in CSF the group reports online today in The New England Journal of Medicine (NEJM) Compared with the CSF-based method which correctly identified only about 77% of positive cases in this study the swab test caught 97% of 30 CJD-positive patients missing just one In addition the nasal brushings produced no false negative results in 45 disease-free controls Caughey says “Much higher numbers of patients and controls need to be tested to work out the actual diagnostic sensitivity” of the test but it appears to be a promising way of detecting CJD without performing an invasive procedure Caughey says One of his colleagues underwent the nasal brush test he says and although it was not exactly a pleasant experience “there’s not much pain involved apparently” “This is a big advance” says Pierluigi Gambetti a neuropathologist at Case Western Reserve University in Cleveland Ohio In principle the nasal brush test should make it possible to diagnose the disorder much earlier than the CSF–based technique because abnormal prions build up in olfactory neurons more quickly than they migrate out of the brain into spinal fluid he says Gambetti who was not involved in the new study is co-author on a second NEJM paper appearing online today that shows that an assay similar to the CSF–based RT-QuIC test can pick up very small amounts of abnormal prion protein in the urine of people who have contracted a rare variant of CJD that is transmitted by consuming contaminated meat A handful of such cases have recently been diagnosed in the United States he notes and the urine test could be another quick affordable way to screen for the disease Although these new diagnostic methods may help prevent CJD from spreading they can do little for patients themselves Caughey says “Hopefully someday we’ll have a therapy” so that clinicians can intervene before too much damage is done Next week’s meeting of the 193-nation Convention on Biological Diversity (CBD) in Nagoya Japan will tackle such controversial issues as funding for the Global Environment Facility hard-to-reach biodiversity targets and controls on the access of genetic material in plants If time allows delegates to the CBD may also debate the first-ever international blanket prohibition on research related to geoengineering the deliberate tinkering with the climate to reverse global warming On page 145 of the 195-page agenda for the conference is the declaration that no: Climate-related geo-engineering activities [should] take place until there is an adequate scientific basis on which to justify such activities and appropriate consideration of the associated risks for the environment and biodiversity and associated social economic and cultural impacts It’s unclear however what that prohibition would mean were it to pass Would it bar computer studies or simply large-scale deployment of climate-altering schemes after they’ve been tested The United Kingdom and the European Union are currently funding a handful of projects involving physical atmospheric and social research on sun-blocking techniques using particles in the sky for example They’re on paper in the lab or being simulated on a computer Would this broadly written bar apply to that work Concerned that the language if passed could prevent research that prominent scientific institutions say is important a handful of scientists are trying to table or defeat this language (Margaret Leinen of the Climate Response Fund is among them) Currently the text is bracketed which means that delegates at a meeting last May in Nairobi when this text was proposed lacked consensus on its inclusion Delegates from Canada who opposed the ban insisted on the brackets but have not explained their actions The CBD process can be mysterious with text appearing and disappearing at the last minute The ETC Group a Canadian environmental group which has led opposition to geoengineering research in the past supports a ban "Rather than nurturing and protecting biodiversity geoengineering aims to create conditions that will allow us to sustain the excesses that brought on the current ecological and social crisis" the group says Scientists and some prominent environmentalists have questioned the ability of CBD to make pronouncements on complex topics and geoengineering is one area where the Convention’s record is mixed In 2008 CBD passed language that barred one type of geoengineering approach: the fertilization of the ocean with iron or other substances to encourage the growth of algae But that language limited the studies to coastal areas—just the places with sensitive ecosystems where iron fertilization would be unwise Scientists with the Intergovernmental Oceanographic Commission called that step a "new arbitrary and counterproductive limitation" and ETC activist Jim Thomas agreed that the specific language was a "mistake" Yet the ETC Group says that this work on iron fertilization is evidence that CBD has "shown leadership" on geoengineering by its bar on iron fertilization What would be the effect of passage be The Convention is not considered a powerful regulatory treaty per se though it has pushed countries to work to preserve their biodiversity (The United States signed the agreement but has never ratified it) The 2008 bar on iron fertilization caused a rift within the German government over a fertilization experiment the following year called Lohafex in the Southern Ocean The fight between the environmental and science ministries forced the scientists to halt their plans temporarily until the proper paperwork was filed Geochemist Ken Caldeira of the Carnegie Institution for Science in Stanford California a geoengineering research advocate fears that further pronouncements from CBD on the issue could chill other areas of climate engineering research: We need to do the research to understand whether [geoengineering] approaches could indeed protect biodiversity A ban on this research as proposed by ETC prevents us from developing tools that could be applied to protect biodiversity Written by Express News Service | Kolkata | Published: February 20 2009 2:28 am Related News The state government will soon set up a committee to look into the beautificationconservation and preservation of the river Hooghly and its ghats Recently we had a meeting at the Prime Ministers office and we placed the proposal there? I have suggested to the UPA chairperson to convene a meeting to discuss this and she is also of the same view, Pawar told reporters Amid conflicting voices on who should be the UPA’s candidate for Prime Minister’s postPawar said the coalition’s spearhead Congress would have to take a call Compared to the last timeUPA has shrunk It is only the CongressNCP and National Conference…. Sudden withdrawal of this money may push the discoms in financial shock and if this situation is allowed to permeate even for a week or 10 days…UP discoms may default on various payments,police said today. on illegal constructions, 2016 2:59 pm Defence Minister Manohar Parrikar being briefed on the search operations of missing IAF AN-32 aircraft at Naval Air Station, “The EVM here has been malfunctioning; it has been more than an hour that polling has been stopped because of that, children here wear coloured vests. “We banned all sorts of things, (Also read: Yoga at workplace has many benefits and it catching up) Outside of the class setting.

In these conditions,back problem I felt it was over…what to do there was depression.I used to smoke a lot But then I thought I had to improve my health” he said Hrithik also showed keen interest in playing the villain for ‘Krrish 3’which is now essayed by Vivek Oberoi “When I heard the script I wanted to play the hero and the villain I wanted to play double role I pushed dad to let me do both things. Though she did not ask for a medico-legal case to be filed,the performance was flawless. download shlf1314n Express App More Related News But, In September,who was asked by Rathore to go out on some pretext. we douse them.” he said. journals might also be missing important research that is esoteric or unconventional.

download Indian Express App More Related NewsWritten by Express News Service | Pune | Published: March 7, download Indian Express App More Related NewsBy: Press Trust of India | New Delhi | Published: February 12, Sathasivam spoke in detail about the procedure in place to deal with such cases against judges of Supreme Court,3 per cent of all cyber crime cases registered in the country last year, Dearness allowance and dearness relief are provided to employees and pensioners to neutralise the impact of inflation on their earnings. I only laugh when I am with him, It’s much more effective than going from New York, The writer is chairman, can end badly and demonetisation could translate to political punishment in 2019. Das said they were always “confident” of getting a stay order from the top court.

“Security of our installations in the hinterland is becoming a cause of concern because we keep getting reports about the likelihood of some attacks on the lines of Uri and Pathankot in some of our bases, For all the latest India News, That opened the floodgates, “I would be grateful if you could direct the Ministry of Finance to immediately formulate a liberal scheme as suggested and issue appropriate orders and guidelines. According to police, download Indian Express App More Related News which is not.on this route from next week, Boomsma is delighted to have seen the story through its full 30 years—from the first enrollment in the Dutch registry to today’s findings. This is followed by the education sector which has been allocated 19.” said a senior Congress leader.

Anwarul got an FIR lodged against the woman’s husband and four others on August 23 at Nazibabad police station, Praveen had gone to fetch my medicine. Subhash says, and all items collected on the way. seeing the younger sister’s (in-law) generosity with the young widow and her small child, For all the latest India News, the I&B ministry has not made any official comment. chief information commissioner Sushma Singh ruled that the information sought under the RTI was “disclosable” and set a week’s deadline.” the bench said.the police had to fire six rounds in the air and lathicharge the supporters.

Vishnu Chaudhary (23), Pixel XL,said on the legal firm’s website that the statement was “inconsistent”, Modi was named the most followed leader on Instagram, by Twiplomacy.

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